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The San Francisco 49ers defeated the Indianapolis Colts 48-27 in a high-scoring Week 16 matchup. Brock Purdy threw five touchdown passes while Christian McCaffrey had 117 rushing yards and two receiving touchdowns. Alec Pierce had a breakout game for Indianapolis with two touchdown catches, but the Colts' five-game losing streak continued.
December 23, 2025
The Pittsburgh Steelers defeated the Detroit Lions 29-24 in a high-scoring Week 16 battle. Jaylen Warren starred with 143 rushing yards and two touchdowns, while Aaron Rodgers threw for 266 yards. Despite Jared Goff's 364-yard passing performance, the Lions fell to 8-7, hurting their playoff chances.
December 22, 2025
The Atlanta Falcons defeated the Arizona Cardinals 26-19 in Week 16, with Bijan Robinson leading the way with 168 total yards from scrimmage and a touchdown. Kirk Cousins threw for 197 yards and two touchdowns while adding a rushing score, while Michael Wilson provided a highlight for Arizona with a 32-yard touchdown catch.
The Tennessee Titans dominated the Kansas City Chiefs 26-9 behind rookie quarterback Cam Ward's stellar 228-yard, 2-touchdown performance. Tony Pollard rushed for 102 yards while Tyjae Spears added two touchdowns as the Titans controlled the game from start to finish.
The Los Angeles Chargers defeated the Dallas Cowboys 34-17 behind Justin Herbert's outstanding 300-yard, 3-touchdown performance and rookie Omarion Hampton's powerful rushing display. George Pickens had a standout game for Dallas with 130 receiving yards, but it wasn't enough to prevent the Cowboys' playoff elimination.
The New Orleans Saints host the struggling New York Jets in Week 16, with the Saints riding a two-game winning streak behind rookie quarterback Tyler Shough's development while the Jets face challenges on both sides of the ball after consecutive blowout losses.
December 21, 2025
The 11-3 Patriots visit the 7-7 Ravens in a crucial AFC matchup. New England seeks to bounce back from their Bills loss with rookie star TreVeyon Henderson leading their explosive offense, while Baltimore rides momentum from shutting out Cincinnati behind Lamar Jackson and Derrick Henry's powerful ground game.
The Los Angeles Chargers (10-4) travel to face the Dallas Cowboys (6-7-1) in a crucial Week 16 matchup. While Dallas averages more points per game, the Chargers have been more consistent winners and are coming off a big victory over Kansas City. The Cowboys desperately need wins to keep playoff hopes alive.
December 20, 2025
The Panthers and Buccaneers face off in Week 16 with identical 7-7 records in a division rivalry game focused on pride rather than playoffs, with Tampa Bay's more consistent offense giving them the advantage.
The 11-3 Los Angeles Rams visit the 11-3 Seattle Seahawks in a crucial NFC West battle. The Rams bring an explosive offense led by Matthew Stafford and Puka Nacua, while Seattle counters with a dominant defense and clutch quarterback play from Sam Darnold. This prime-time showdown will likely determine the division winner and playoff seeding.
December 17, 2025